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TTI1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501565172
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50-156-5172 10 μL
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Catalog No. 50-156-5172 Supplier Bethyl Laboratories, Inc Supplier No. A303452AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Specifications

Antigen TTI1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene TTI1
Gene Accession No. O43156
Gene Alias KIAA0406, smg-10, TEL2-interacting protein 1 homolog, Tel two interacting protein 1, Tel2 interacting protein 1 homolog, smg-10 homolog, nonsense mediated mRNA decay factor
Gene Symbols TTI1
Host Species Rabbit
Immunogen Between 1039 and 1089
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9675
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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