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TTI1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501733853 Shop All Proteintech Group Inc Products
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50-173-3853 150 μL
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Catalog No. 50-173-3853 Supplier Proteintech Group Inc Supplier No. 223811AP150UL
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Description

Rabbit Polyclonal Antibody

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Specifications

Antigen TTI1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TTI1
Gene Accession No. O43156
Gene Alias KIAA0406, TTI1
Gene Symbols TTI1
Host Species Rabbit
Immunogen TTI1 Fusion Protein Ag17697
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9675
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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