Invitrogen™ TTI2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554812

Catalog No. PIPA554812

Description

Immunogen sequence: LLGKVETAKN SLVGPAWQTG LHHLAGPVYI FAITHSLEQP WTTPRSREVA REVLTSLLQV TECGSVAGFL HGENEDEKG Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 70%.

The DNA replication (origin) licensing system is necessary for duplicating the genome in each cell cycle. Geminin is a protein that prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during G1 phase and accumulates during S, G2, and M phases of mitosis. It is then degraded during the metaphase-anaphase trasition allowing replication to occur during subsequent cycles. Geminin has also been implicated in maintaining integrity of the male germline genome.

Specifications

• Antigen: TTI2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTI2
• Gene Alias: C8orf41; FLJ23263; MRT39; RGD1310414; Tel2 interacting protein 2 homolog; TELO2 interacting protein 2; TELO2-interacting protein 2; TTI2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80185
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6NXR4
• Gene Symbols: TTI2
• Immunogen: Recombinant protein corresponding to Human TTI2. Recombinant protein control fragment (Product #RP-93782).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG