Invitrogen™ TTK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119893

Catalog No. PIPA5119893

Description

Positive Control: Human placenta tissue lysates, human lung tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, SH-SY5Y, MG-63. Subcellular Location: Spindle, nucleus, cytoplasm, kinetochore, membrane.

TTK is a serine/threonine kinase closely related to SPK1, PIM 1 and CDC2 serine/threonine kinases. TTK is a dual-specificity kinase, which can also phosphorylate tyrosine. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. TTK encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: TTK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTK
• Gene Alias: AL022661; cancer/testis antigen 96; CT96; Dual specificity protein kinase TTK; esk; Esk1; monopolar spindle 1 kinase; monopolar spindle 1-like 1; MPH1; MPS1; MPS1L1; OTTHUMP00000016778; OTTHUMP00000220743; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase; PYT; TTK; Ttk protein kinase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7272
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P33981
• Gene Symbols: TTK
• Immunogen: Recombinant protein within human TTK aa 1-300.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG