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Invitrogen™ TTK Polyclonal Antibody
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Catalog No. PIPA5119893
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100 μL
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PIPA5119893 100 μL
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Catalog No. PIPA5119893 Supplier Invitrogen™ Supplier No. PA5119893
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Description

Rabbit Polyclonal Antibody

Positive Control: Human placenta tissue lysates, human lung tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, SH-SY5Y, MG-63. Subcellular Location: Spindle, nucleus, cytoplasm, kinetochore, membrane.

TTK is a serine/threonine kinase closely related to SPK1, PIM 1 and CDC2 serine/threonine kinases. TTK is a dual-specificity kinase, which can also phosphorylate tyrosine. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. TTK encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTK
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 50% glycerol, 1% BSA and 0.05% sodium azide; pH 7.4
Gene TTK
Gene Accession No. P33981
Gene Alias AL022661; cancer/testis antigen 96; CT96; Dual specificity protein kinase TTK; esk; Esk1; monopolar spindle 1 kinase; monopolar spindle 1-like 1; MPH1; MPS1; MPS1L1; OTTHUMP00000016778; OTTHUMP00000220743; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase; PYT; TTK; Ttk protein kinase
Gene Symbols TTK
Host Species Rabbit
Immunogen Recombinant protein within human TTK aa 1-300.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7272
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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