Invitrogen™ TTLL12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551810

Catalog No. PIPA551810

Description

Immunogen sequence: DYEKHFTVMN YDPDVVLKQV HCEEFIPEFE KQYPEFPWTD VQAEIFRAFT ELFQVACAKP PPLGLCDYPS SRAMYAVDLM LKWDNGPDGR RVMQPQILEV NFNPDCERAC RYHPTFFNDV FSTLFLDQPG Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 85%.

TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.

Specifications

• Antigen: TTLL12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTLL12
• Gene Alias: BC055368; D430005B17; dJ526I14.2; Inactive tubulin--tyrosine ligase-like protein 12; KIAA0153; RGD1305319; TTL domain protein; ttll12; tubulin tyrosine ligase like 12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; tubulin--tyrosine ligase-like protein 12
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14166
• Gene Symbols: TTLL12
• Immunogen: Recombinant protein corresponding to Human TTLL12. Recombinant protein control fragment (Product #RP-91500).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov