Invitrogen™ TTLL12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531740

Catalog No. PIPA531740

Description

Recommended positive controls: Raji, NCI-H929, NIH-3T3. Predicted reactivity: Mouse (91%), Rat (89%), Chicken (81%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.

Specifications

• Antigen: TTLL12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTLL12
• Gene Alias: BC055368; D430005B17; dJ526I14.2; Inactive tubulin--tyrosine ligase-like protein 12; KIAA0153; RGD1305319; TTL domain protein; ttll12; tubulin tyrosine ligase like 12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; tubulin--tyrosine ligase-like protein 12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 223723, 23170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14166, Q3UDE2
• Gene Symbols: TTLL12
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human TTLL12. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov