Invitrogen™ TTLL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532022

Catalog No. PIPA532022

Description

Recommended positive controls: NT2D1, PC-3. Predicted reactivity: Mouse (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4. Also acts as a monoglutamylase: generates monoglutamylation of CGAS, leading to impair the nucleotidyltransferase activity of CGAS. [UniProt].

Specifications

• Antigen: TTLL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTLL4
• Gene Alias: KIAA0173; TTLL4; Tubulin polyglutamylase TTLL4; tubulin tyrosine ligase like 4; tubulin tyrosine ligase-like family member 4; tubulin tyrosine ligase-like family, member 4; tubulin--tyrosine ligase-like protein 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9654
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14679
• Gene Symbols: TTLL4
• Immunogen: Recombinant fragment corresponding to a region within amino acids 567 and 798 of Human TTLL4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG