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Invitrogen™ TTLL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532022

Catalog No. PIPA532022


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Description

Description

Recommended positive controls: NT2D1, PC-3. Predicted reactivity: Mouse (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4. Also acts as a monoglutamylase: generates monoglutamylation of CGAS, leading to impair the nucleotidyltransferase activity of CGAS. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TTLL4
Polyclonal
Unconjugated
TTLL4
KIAA0173; TTLL4; Tubulin polyglutamylase TTLL4; tubulin tyrosine ligase like 4; tubulin tyrosine ligase-like family member 4; tubulin tyrosine ligase-like family, member 4; tubulin--tyrosine ligase-like protein 4
Rabbit
Antigen affinity chromatography
RUO
9654
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Q14679
TTLL4
Recombinant fragment corresponding to a region within amino acids 567 and 798 of Human TTLL4.
100 μL
Primary
Human
Antibody
IgG
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