TTR Mouse anti-Human, Clone:2E10C5, Abnova™

Catalog No.	Quantity
89-333-147	100 μg

Catalog No. 89-333-147 Supplier Abnova Corporation Supplier No. MAB16697

Description

Mouse monoclonal antibody raised against recombinant human TTR.

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq]

Specifications

• Antigen: TTR
• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 2E10C5
• Conjugate: Unconjugated
• Description: transthyretin
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: TTR
• Gene Alias: HsT2651, PALB, TBPA
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 1-147 of human TTR from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 7276
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1