Invitrogen™ TTYH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562229

Catalog No. PIPA562229

Description

Immunogen sequence: SDFCSNPDPY VLNLTQEETG LSSDILSYYL LCNRAVSNPF QQRLTLSQRA LANIHSQLLG LEREAVPQFP SAQKPLLSLE ETLNVTEGNF HQLVALLHCR SLHKDYGAAL Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.

Specifications

• Antigen: TTYH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTYH1
• Gene Alias: 4930459B04Rik; 6330408P11Rik; hTTY1; mTTY1; Protein tweety homolog 1; tty; TTY1; TTYH1; tweety family member 1; tweety homolog 1; tweety homolog 1 (Drosophila)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57348
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H313
• Gene Symbols: TTYH1
• Immunogen: Recombinant protein corresponding to Human TTYH1. Recombinant protein control fragment (Product #RP-103083).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG