Invitrogen™ TUBA1A Polyclonal Antibody

Catalog No.	Quantity
PIPA585418	100 μL

Catalog No. PIPA585418 Supplier Invitrogen™ Supplier No. PA585418

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (99%), Xenopus laevis (98%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Positive Control: 293T, A431, Jurkat, Raji, NIH-3T3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

Specifications

• Antigen: TUBA1A
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 0.24 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene: TUBA1A
• Gene Accession No.: P68369, Q71U36
• Gene Alias: alpha 1a antibody; alpha 3 antibody; alpha-tubulin; alpha-tubulin 1; Alpha-tubulin 3; alpha-tubulin 3 antibody; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; B-ALPHA-1 antibody; brain-specific antibody; Detyrosinated tubulin alpha-1A chain; FLJ25113 antibody; FLJ30169; H2 ALPHA; H2ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub1 antibody; hum-a-tub2; hum-a-tub2 antibody; LIS3; LIS3 antibody; LOC106557476; M40; MGC117247; MGC16435; OK/SW cl.56; OK/SWcl.56; OK/SW-cl.56; Talpha1 alpha-tubulin; TUBA1; Tuba-1; Tuba1a; TUBA1A antibody; TUBA3; TUBA3 antibody; TUBA6; TUBB1; TUBB5; tubulin alpha 1a; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-1A chain antibody; tubulin alpha-3 chain; tubulin alpha-3 chain antibody; Tubulin B-alpha-1; tubulin B-alpha-1 antibody; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1A; tubulin, alpha 6; tubulin, alpha, brain-specific; unnamed protein product
• Gene Symbols: TUBA1A
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human alpha Tubulin 1A. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22142, 7846
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov