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Invitrogen™ TUBA3C/TUBA3E Polyclonal Antibody
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Catalog No. PIPA5106805
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100 μL
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PIPA5106805 100 μL
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Catalog No. PIPA5106805 Supplier Invitrogen™ Supplier No. PA5106805
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TUBA3C/E.

The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). Microtubules have their intrinsic polarity; highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening - this phenomenon is called dynamic instability of microtubules. The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes).
TRUSTED_SUSTAINABILITY

Specifications

Antigen TUBA3C/TUBA3E
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TUBA3C
Gene Accession No. P0DPH7, Q6PEY2
Gene Alias alpha-tubulin 2; alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; bA408E5.3; B-ALPHA-1; Detyrosinated tubulin alpha-3C chain; Detyrosinated tubulin alpha-3D chain; Detyrosinated tubulin alpha-3E chain; hum-a-tub1; hum-a-tub2; LIS3; TUBA2; TUBA3; TUBA3C; TUBA3C/E; TUBA3D; TUBA3E; tubulin alpha 3c; tubulin alpha 3e; tubulin alpha-2 chain; Tubulin alpha-3C chain; tubulin alpha-3C/D chain; Tubulin alpha-3D chain; Tubulin alpha-3E chain; tubulin B-alpha-1; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e
Gene Symbols TUBA3C, TUBA3E
Host Species Rabbit
Immunogen A synthesized peptide derived from human TUBA3C/E, corresponding to a region within C-terminal amino acids.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 112714, 7278
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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