TUBA4A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA529546

Catalog No. PIPA529546

Description

PA5-29546 targets alpha Tubulin 4a in IF and WB applications and shows reactivity with Human and mouse samples. The PA5-29546 immunogen is recombit fragment corresponding to a region within amino acids 154 and 440 of Human alpha Tubulin 4a. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predomitly found in morphologically differentiated neurologic cells.

Specifications

• Antigen: alpha Tubulin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q5XIF6, P68366, P68368
• Gene Symbols: TUBA4A
• Immunogen: Recombit fragment corresponding to a region within amino acids 154 and 440 of Human alpha Tubulin 4a
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 0.44 mg/mL
• Gene: TUBA4A
• Gene Alias: H2-ALPHA, TUBA1, tubulin H2-alpha, tubulin alpha-1 chain, tubulin alpha-4A chain, tubulin, alpha 1 (testis specific)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22145, 316531, 478918, 7277
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid