Invitrogen™ TUBA4A Polyclonal Antibody

Catalog No.	Quantity
PIPA5100996	100 μL

Catalog No. PIPA5100996

Supplier: Invitrogen™ PA5100996

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total alpha Tubulin 4A.

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa, are homologous but not identical. The alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

Specifications

• Antigen: TUBA4A
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: TUBA4A
• Gene Accession No.: P68366, P68368, Q5XIF6
• Gene Alias: Alpha-tubulin 1; Alpha-tubulin 4; alpha-tubulin isotype M-alpha-4; ALS22; H2-ALPHA; M[a]4; Testis-specific alpha-tubulin; TUBA1; Tuba4; TUBA4A; Tubulin alpha; tubulin alpha 4a; tubulin alpha-1 chain; Tubulin alpha-4 chain; tubulin alpha-4A chain; Tubulin H2-alpha; tubulin, alpha 1 (testis specific); tubulin, alpha 4; tubulin, alpha 4a
• Gene Symbols: TUBA4A
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human TUBA4A(Accession P68366), corresponding to amino acid residues V14-R64.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22145, 316531, 7277
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov