Tunicamycin, 95%

Description

CAS: 11089-65-9 | C₃₉H₆₄N₄O₁₆

Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during dolichol-linked glycoprotein synthesis. Dose-dependent inhibition of DNA synthesis may be related to the alteration of glycoproteins, which thereby affects the transport of thymidine into cells. Additionally, tunicamycin has been reported to prevent cell cycle progression in primary cultures of rat glial cells, as well as inhibit lipid-mediated protein glycosylation in chick or mouse fibroblasts in a dose-dependent manner.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during d

Specifications

Chemical Identifiers

• CAS: 11089-65-9
• Molecular Formula: C₃₉H₆₄N₄O₁₆
• MDL Number: MFCD00065709

• Type: Tunicamycin
• Physical Form: Powder
• Color: White to Yellow
• Quantity: 10 mg
• Sensitivity: Light and moisture sensitive
• UN Number: UN3462
• Beilstein: 6888090
• Merck Index: 14,9819
• Solubility Information: Soluble in methanol, ethanol, DMSO, or DMF
• Formula Weight: 844.95
• Percent Purity: 95%
• Chemical Name or Material: Tunicamycin

Safety and Handling

Hazard Category	H300+H330-H373
Hazard Statement	GHS H Statement H300-H330-H373 Fatal if swallowed. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statement	P260-P264b-P270-P271-P284-P301+P310-P304+P340-P310-P314-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
RTECSNumber	YO7980200
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only