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Tunicamycin, 95%
Description
Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during dolichol-linked glycoprotein synthesis. Dose-dependent inhibition of DNA synthesis may be related to the alteration of glycoproteins, which thereby affects the transport of thymidine into cells. Additionally, tunicamycin has been reported to prevent cell cycle progression in primary cultures of rat glial cells, as well as inhibit lipid-mediated protein glycosylation in chick or mouse fibroblasts in a dose-dependent manner.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during d
Specifications
Specifications
| Type | Tunicamycin |
| Physical Form | Powder |
| Color | White to Yellow |
| Quantity | 10 mg |
| Sensitivity | Light and moisture sensitive |
| UN Number | UN3462 |
| Beilstein | 6888090 |
| Merck Index | 14,9819 |
| Solubility Information | Soluble in methanol, ethanol, DMSO, or DMF |
| Formula Weight | 844.95 |
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Safety and Handling
| Hazard Category | H300+H330-H373 |
| Hazard Statement | GHS H Statement H300-H330-H373 Fatal if swallowed. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure. |
| Precautionary Statement | P260-P264b-P270-P271-P284-P301+P310-P304+P340-P310-P314-P330-P501c |
| DOTInformation | Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S. |
| RTECSNumber | YO7980200 |
| TSCA | No |
| Recommended Storage | Keep cold |
RUO – Research Use Only
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