Invitrogen™ TUSC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110993

Catalog No. PIPA5110993

Description

Immunogen sequence: SGSKARGLWP FASAAGGGGS EAAGAEQALV RPRGRAVPPF VFTRRGSMFY DEDGDLAHEF YEETIVTKNG QKRAKLRRVH KNLIPQGIVK LDHPRIHVDF PVI.

TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.

Specifications

• Antigen: TUSC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TUSC2
• Gene Alias: 1190001E22Rik; AA407686; C3orf11; Fus1; Fus-1 protein; Fusion 1 protein; Lgcc; lung cancer candidiate, FUS; PAP; PDAP2; PDGFA associated protein 2; PDGFA-associated protein 2; Tumor suppressor candidate 2; TUSC 2; Tusc2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11334
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75896
• Gene Symbols: TUSC2
• Immunogen: Recombinant Protein corresonding to Human TUSC2. Recombinant protein control fragment (Product #RP-95276).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG