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Invitrogen™ TUSC2 Polyclonal Antibody
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Catalog No. PIPA5110993
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100 μL
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PIPA5110993 100 μL
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Catalog No. PIPA5110993 Supplier Invitrogen™ Supplier No. PA5110993
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SGSKARGLWP FASAAGGGGS EAAGAEQALV RPRGRAVPPF VFTRRGSMFY DEDGDLAHEF YEETIVTKNG QKRAKLRRVH KNLIPQGIVK LDHPRIHVDF PVI Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 93%.

TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TUSC2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TUSC2
Gene Accession No. O75896
Gene Alias 1190001E22Rik; AA407686; C3orf11; Fus1; Fus-1 protein; Fusion 1 protein; Lgcc; lung cancer candidiate, FUS; PAP; PDAP2; PDGFA associated protein 2; PDGFA-associated protein 2; Tumor suppressor candidate 2; TUSC 2; Tusc2
Gene Symbols TUSC2
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human TUSC2. Recombinant protein control fragment (Product #RP-95276).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11334
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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