TUSC2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6736	100 μL

Catalog No. 50-198-6736 Supplier Bioss Supplier No. BS5707R

Description

Rabbit Polyclonal Antibody

TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.

Specifications

• Antigen: TUSC2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: TUSC2
• Gene Accession No.: O75896
• Gene Alias: 1190001E22Rik; AA407686; C3orf11; FUS1; Fus-1 protein; Fusion 1 protein; LGCC; lung cancer candidiate, FUS; PAP; Pdap2; PDGFA associated protein 2; PDGFA-associated protein 2; Tumor suppressor candidate 2; TUSC 2; TUSC2
• Gene Symbols: TUSC2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human TUSC2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11334
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG