Invitrogen™ TUT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550151

Catalog No. PA550151

Description

The antibody detects endogenous levels of total TUT1 protein.

TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).[supplied by OMIM].

Specifications

• Antigen: TUT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TUT1
• Gene Alias: 2700038E08Rik; FLJ21850; FLJ22267; FLJ22347; MGC131987; MGC149809; nuclear speckle targeted phosphatidylinositol 4-phosphate 5-kinase type I-alpha regulated-poly(A) polymerase; nuclear speckle-targeted PIPK1A-regulated-poly(A) polymerase; PAP-associated domain-containing 2; PAPD2; poly(A) polymerase associated domain containing 2; RBM21; RNA binding motif protein 21; RNA uridylyltransferase; RNA-binding motif protein 21; RNA-binding protein 21; speckle targeted PIP5K1A-regulated poly(A) polymerase; STARPAP; Star-PAP; terminal uridylyl transferase 1 U6 snRNA-specific; terminal uridylyl transferase 1, U6 snRNA-specific; Tut1; TUTase; TUTase 6; TUTase6; U6 snRNA-specific terminal uridylyltransferase 1; U6 snRNA-specific terminal uridylyltransferase 1; speckle targeted PIP5K1A-regulated poly(A) polymerase; U6 TUTase; U6-TUTase; up-regulated in lung cancer 6; URLC6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64852, 70044
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8R3F9, Q9H6E5
• Gene Symbols: TUT1
• Immunogen: Synthesized peptide derived from internal of human TUT1 (aa 291-340).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG