Invitrogen™ TUT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567204

Catalog No. PIPA567204

Description

Immunogen sequence: LASPQSLPPAS PLLEDREEGD LGKASELAET PKEEKAEGAA MLELVGSILR GCVPGVYRVQ TVPSARRPVV KFCHRPSGLH GD Highest antigen sequence identity to the following orthologs - mouse 81%, rat 80%.

TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).[supplied by OMIM].

Specifications

• Antigen: TUT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TUT1
• Gene Alias: 2700038E08Rik; FLJ21850; FLJ22267; FLJ22347; MGC131987; MGC149809; nuclear speckle targeted phosphatidylinositol 4-phosphate 5-kinase type I-alpha regulated-poly(A) polymerase; nuclear speckle-targeted PIPK1A-regulated-poly(A) polymerase; PAP-associated domain-containing 2; PAPD2; poly(A) polymerase associated domain containing 2; RBM21; RNA binding motif protein 21; RNA uridylyltransferase; RNA-binding motif protein 21; RNA-binding protein 21; speckle targeted PIP5K1A-regulated poly(A) polymerase; STARPAP; Star-PAP; terminal uridylyl transferase 1 U6 snRNA-specific; terminal uridylyl transferase 1, U6 snRNA-specific; Tut1; TUTase; TUTase 6; TUTase6; U6 snRNA-specific terminal uridylyltransferase 1; U6 snRNA-specific terminal uridylyltransferase 1; speckle targeted PIP5K1A-regulated poly(A) polymerase; U6 TUTase; U6-TUTase; up-regulated in lung cancer 6; URLC6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64852
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H6E5
• Gene Symbols: TUT1
• Immunogen: Recombinant Human TUT1. Recombinant protein control fragment (Product #RP-107840).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov