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TWIST1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501734921 Shop All Proteintech Group Inc Products
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50-173-4921 150 μL
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Catalog No. 50-173-4921 Supplier Proteintech Group Inc Supplier No. 254651AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody reacts specifically with TWIST1 protein.

TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.

Specifications

Antigen TWIST1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TWIST1
Gene Accession No. P26687, Q15672
Gene Alias ACS3, bHLHa38, BPES2, BPES3, H twist, SCS, TWIST, twist homolog 1 (Drosophila), Twist related protein 1, TWIST1
Gene Symbols TWIST1
Host Species Rabbit
Immunogen TWIST1-specific Fusion Protein Ag21924
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22160, 7291
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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