Invitrogen™ TWIST2 Monoclonal Antibody (1A11D9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531944

Catalog No. PIMA531944

Description

MA5-31944 has been tested in indirect ELISA.

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Specifications

• Antigen: TWIST2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q8WVJ9
• Gene Symbols: TWIST2
• Immunogen: Purified recombinant fragment of human TWIST2 (AA: 1-160) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 1A11D9
• Conjugate: Unconjugated
• Gene: TWIST2
• Gene Alias: AMS; BBRSAY; bHLHa39; Class A basic helix-loop-helix protein 39; dermis expressed 1; dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; SETLSS; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 2; twist homolog 2; TWIST2; twist-related bHLH protein Dermo1; twist-related protein 2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 117581
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid