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Invitrogen™ TWIST2 Polyclonal Antibody
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Catalog No. PIPA599393
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100 μL
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PIPA599393 100 μL
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Catalog No. PIPA599393 Supplier Invitrogen™ Supplier No. PA599393
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Twist2.

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TWIST2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TWIST2
Gene Accession No. P97831, Q8WVJ9, Q9D030
Gene Alias AMS; BBRSAY; bHLHa39; Class A basic helix-loop-helix protein 39; dermis expressed 1; dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; SETLSS; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 2; twist homolog 2; TWIST2; twist-related bHLH protein Dermo1; twist-related protein 2
Gene Symbols TWIST2
Host Species Rabbit
Immunogen A synthesized peptide derived from human TWIST2(Accession Q8WVJ9), corresponding to amino acid residues S10-S60.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117581, 13345, 59327
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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