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TWSG1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981511
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100 μL
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50-198-1511 100 μL
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Catalog No. 50-198-1511 Supplier Bioss Supplier No. BS11606R
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Description

Rabbit Polyclonal Antibody

TWSG1 may be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.

Specifications

Antigen TWSG1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Twsg1
Gene Accession No. Q9GZX9
Gene Alias 1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403e; PSEC0250; TSG; Twg; twisted gastrulation BMP signaling modulator 1; twisted gastrulation homolog 1; twisted gastrulation homolog 1 (Drosophila); Twisted gastrulation protein homolog 1; Twsg1
Gene Symbols Twsg1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TWSG1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57045
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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