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TXNIP Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549279

Catalog No. PA549279


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Description

Description

Predicted to react with rat based on sequence homology.

Thioredoxin-interacting protein belongs to the arrestin family. It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1beta.
Specifications

Specifications

Txnip
Polyclonal
PBS with 0.09% sodium azide
Q8BG60
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
56338
Western Blot
Unconjugated
Txnip
Liquid
TXNIP
KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse
Documents
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