Invitrogen™ TXNL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596468

Catalog No. PIPA596468

Description

Immunogen sequence: MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGELI GGLDIIKELE ASEELDTICP KAPKLEERLK VLTNKASVML FMKGNKQEAK CGFSKQILEI LNSTGVEYET FDILEDEEVR QGLKAYSNWP TYPQLYVKGE LVGGLDIVKE LKENGELLPI LRGEN; Positive Samples: Raji, MCF-7, A-431, HeLa; Cellular Location: Cytoplasm, Z line, cell cortex, myofibril, sarcomere.

This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.

Specifications

• Antigen: TXNL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLRX3
• Gene Alias: bA500G10.4; FLJ11864; Glrx3; GLRX4; glutaredoxin 3; glutaredoxin 4; glutaredoxin-3; GRX3; GRX4; HUSSY-22; Picot; PKC interacting cousin of thioredoxin; PKC-interacting cousin of thioredoxin; PKCq-interacting protein; PKC-theta-interacting protein; testicular tissue protein Li 75; thioredoxin-like 2; thioredoxin-like protein 2; TXNL2; TXNL3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10539
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 1.72 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O76003
• Gene Symbols: GLRX3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human GLRX3 (NP_0011867971).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov