TXNRD1 Mouse anti-Human, Mouse, Rat, Clone: OTI5G3, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0609	100 μg

Catalog No. 50-167-0609 Supplier OriGene Supplier No. CF811365

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Specifications

• Antigen: TXNRD1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5G3
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: TXNRD1
• Gene Accession No.: O89049, Q16881, Q9JMH6
• Gene Alias: GRIM-12, TR, TR1, TRXR1, TXNR
• Gene Symbols: Txnrd1
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TXNRD1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 50493, 58819, 7296
• Target Species: Human, Mouse, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1