TYR Monoclonal Antibody (OTI1F3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA801362

Catalog No. 50-167-8807

Description

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3′ half of this gene.

Specifications

• Antigen: TYR
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P14679
• Gene Symbols: TYR
• Immunogen: Human recombit protein fragment corresponding to amino acids 19-320 of human TYR produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1F3
• Conjugate: Unconjugated
• Gene: TYR
• Gene Alias: ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7299
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid