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Invitrogen™ TYRO3 Monoclonal Antibody (10E11)
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Catalog No. PIMA515505
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PIMA515505 100 μL
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Catalog No. PIMA515505 Supplier Invitrogen™ Supplier No. MA515505
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Description

Mouse Monoclonal Antibody

MA5-15505 targets TYRO3 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15505 immunogen is purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line. MA5-15505 detects TYRO3 which has a predicted molecular weight of approximately 96.9kDa.

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYRO3
Applications ELISA, Western Blot
Classification Monoclonal
Clone 10E11
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene TYRO3
Gene Accession No. Q06418
Gene Alias AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; etk2/tyro3; FLJ16467; Rek; Rse; Sky; soluble tyro 3; soluble tyro3; styro 3; styro3; TIF; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Gene Symbols TYRO3
Host Species Mouse
Immunogen Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7301
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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