TYRO3 Mouse anti-Human, Biotin, Clone: OTI5B4, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA700226

Catalog No. 50-167-7742

Description

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, and cytoskeleton reorganization.

Specifications

• Antigen: TYRO3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: Q06418
• Gene Symbols: TYRO3
• Immunogen: Full length human recombit protein of human TYRO3 produced in HEK293T cell.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: OTI5B4
• Conjugate: Biotin
• Gene: TYRO3
• Gene Alias: BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7301
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid