TYRO3 Mouse anti-Human, Clone: OTI5B4, liquid, TrueMAB™

Catalog No.	Quantity
50-167-7291	100 μg

Catalog No. 50-167-7291 Supplier OriGene Supplier No. TA600225

Description

Mouse Monoclonal Antibody

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, and cytoskeleton reorganization.

Specifications

• Antigen: TYRO3
• Classification: Monoclonal
• Clone: OTI5B4
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with <5% trehalose and 0.05% sodium azide
• Gene: TYRO3
• Gene Accession No.: Q06418
• Gene Alias: BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif
• Gene Symbols: TYRO3
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TYRO3 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7301
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1