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TYRO3 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA528682
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PIPA528682 100 μL
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Catalog No. PIPA528682 Supplier Thermo Scientific Supplier No. PA528682

Description

Rabbit Polyclonal Antibody

Recommended positive controls: TYRO3 tansfected 293T cell. Predicted reactivity: Mouse (91%), Rat (92%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYRO3
Applications Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene TYRO3
Gene Accession No. Q06418
Gene Alias AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; etk2/tyro3; FLJ16467; Rek; Rse; Sky; soluble tyro 3; soluble tyro3; styro 3; styro3; TIF; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Gene Symbols TYRO3
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 497 and 890 of Human TYRO3
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7301
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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