Invitrogen™ TYROBP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA526861

Catalog No. PIPA526861

Description

This antibody is predicted to react with bovine based on sequence homology.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Specifications

• Antigen: TYROBP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYROBP
• Gene Alias: DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7305
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: O43914
• Gene Symbols: TYROBP
• Immunogen: KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TYROBP.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov