Invitrogen™ TYROBP Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142466

Catalog No. PIPA5142466

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_003323.1; NP_937758.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Specifications

• Antigen: TYROBP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYROBP
• Gene Alias: DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 7305
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43914
• Gene Symbols: TYROBP
• Immunogen: Peptide with sequence C-KQRITETESPYQE.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG