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Invitrogen™ TYROBP Recombinant Rabbit Monoclonal Antibody (JG38-70)
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Catalog No. PIMA534787
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100 μL
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Catalog No. Quantity
PIMA534787 100 μL
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Catalog No. PIMA534787 Supplier Invitrogen™ Supplier No. MA534787
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: THP-1, K562, human lung cancer tissue.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYROBP
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JG38-70
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene TYROBP
Gene Accession No. O43914
Gene Alias DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp
Gene Symbols TYROBP
Host Species Rabbit
Immunogen Recombinant protein within Human DAP12 aa 1-113.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7305
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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