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Tyrosinase Ab-1 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS800B Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
12 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Ready-to-Use
Concentration:
1mg/mL
200μg/mL
Prediluted
10 product options available for selection
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Catalog No. Quantity Conjugate Form Concentration
MS800B 1 mL Biotin Concentrated 200μg/mL
MS800P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS800PABX 200 μL Unconjugated Concentrated 1mg/mL
MS800P1 500 μL Unconjugated Concentrated 200μg/mL
MS800P 1 mL Unconjugated Concentrated 200μg/mL
MS800RQ 12 mL Unconjugated Ready-to-Use Prediluted
MS800B0 100 μL Biotin Concentrated 200μg/mL
MS800B1 500 μL Biotin Concentrated 200μg/mL
MS800P0 100 μL Unconjugated Concentrated 200μg/mL
MS800R1 1 mL Unconjugated Prediluted Prediluted
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Catalog No. MS800B Supplier Epredia Supplier No. MS800B

Description

Provide accurate, reproducible results with the Epredia™ Tyrosinase Ab-1, Mouse Monoclonal Antibody.

Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

Host Species: Mouse

Clone: T311

Isotype: IgG2a

Species Reactivity: Human, Dog and Cat. Weakly cross-reacts with Mouse. Others not known.

Epitope: aa 1-433

Immunogen: Recombinant tyrosinase protein

Molecular Weight: 70-80kDa

Positive Control: Melanoma cell lines and Melanoma

Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Staining of melanomas with Ab-1 showed tyrosinase in melanotic as well as amelanotic variants. Ab-1 is a useful marker for melanocytes and melanomas. Occasionally a minor band at 55kDa is also detected in Western Blotting

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunocytology

Specifications

Antigen Tyrosinase Ab-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone T311
Concentration 200μg/mL
Conjugate Biotin
Host Species Mouse
Immunogen Recombinant tyrosinase protein
Quantity 1 mL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Canine, Feline, Human
Form Concentrated
Isotype IgG2a
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