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Tyrosinase Ab-1 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS800P0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
12 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Ready-to-Use
Concentration:
1mg/mL
200μg/mL
Prediluted
10 product options available for selection
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Catalog No. Quantity Conjugate Form Concentration
MS800P0 100 μL Unconjugated Concentrated 200μg/mL
MS800P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS800PABX 200 μL Unconjugated Concentrated 1mg/mL
MS800P1 500 μL Unconjugated Concentrated 200μg/mL
MS800P 1 mL Unconjugated Concentrated 200μg/mL
MS800RQ 12 mL Unconjugated Ready-to-Use Prediluted
MS800B0 100 μL Biotin Concentrated 200μg/mL
MS800B1 500 μL Biotin Concentrated 200μg/mL
MS800B 1 mL Biotin Concentrated 200μg/mL
MS800R1 1 mL Unconjugated Prediluted Prediluted
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Catalog No. MS800P0 Supplier Epredia Supplier No. MS800P0

Description

Provide accurate, reproducible results with the Epredia™ Tyrosinase Ab-1, Mouse Monoclonal Antibody.

Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

Host Species: Mouse

Clone: T311

Isotype: IgG2a

Species Reactivity: Human, Dog and Cat. Weakly cross-reacts with Mouse. Others not known.

Epitope: aa 1-433

Immunogen: Recombinant tyrosinase protein

Molecular Weight: 70-80kDa

Positive Control: Melanoma cell lines and Melanoma

Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Staining of melanomas with Ab-1 showed tyrosinase in melanotic as well as amelanotic variants. Ab-1 is a useful marker for melanocytes and melanomas. Occasionally a minor band at 55kDa is also detected in Western Blotting

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunocytology

Specifications

Antigen Tyrosinase Ab-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone T311
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant tyrosinase protein
Quantity 100 μL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Canine, Feline, Human
Form Concentrated
Isotype IgG2a
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