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Invitrogen™ Tyrosinase Polyclonal Antibody
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Catalog No. PIPA599493
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100 μL
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PIPA599493 100 μL
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Catalog No. PIPA599493 Supplier Invitrogen™ Supplier No. PA599493
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Tyrosinase.

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tyrosinase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TYR
Gene Accession No. P11344, P14679
Gene Alias albino; albino locus protein; ATN; C; CMM8; LB24-AB; monophenol monooxygenase; Oca1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; skc35; Tumor rejection antigen AB; TYR; Tyrosinase; tyrosinase (oculocutaneous albinism IA); tyrosinase precursor
Gene Symbols TYR
Host Species Rabbit
Immunogen A synthesized peptide derived from human TYR(Accession P14679), corresponding to amino acid residues A481-L529.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22173, 308800, 7299
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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