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TYRP1 Antibody (TA99), FITC, Novus Biologicals™
SDP

Catalog No. NB006390 Shop All R&D Systems Products
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NB006390 0.1 mL
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Catalog No. NB006390 Supplier Novus Biologicals Supplier No. NBP234720F
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Description

Mouse Monoclonal Antibody

TYRP1 Monoclonal specifically detects TYRP1 in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen, Flow (Intracellular).

Specifications

Antigen TYRP1
Applications Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone TA99
Conjugate FITC
Dilution Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Formulation PBS with 0.05% Sodium Azide
Gene Alias b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP
Gene Symbols TYRP1
Host Species Mouse
Immunogen SK-MEL-23 cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Test Specificity It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Target Species Human, Mouse
Content And Storage Store at 4°C in the dark.
Isotype IgG2a κ
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