Invitrogen™ TYW1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553065

Catalog No. PIPA553065

Description

Immunogen sequence: KEQQEEKSGL FRNMGRNEDG ERRAMITPAL REALTKQVDA PRERSLLQTH ILW Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 49%.

Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. Wybutosine functions to stabilize codon-anticodon interactions during ribosome decoding and therefore supports the maintenance of the reading frame. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. [provided by RefSeq, Apr 2014].

Specifications

• Antigen: TYW1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYW1B
• Gene Alias: LINC00069; long intergenic non-protein coding RNA 69; MGC87315; NCRNA00069; radical S-adenosyl methionine and flavodoxin domain-containing protein 2; radical S-adenosyl methionine and flavodoxin domains 1; RSAFD2; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B; tRNA wybutosine-synthesizing protein 1 homolog B; tRNA-yW synthesizing protein 1 homolog B; tRNA-yW synthesizing protein 1 homolog B (non-protein coding); TYW1B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 441250
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6NUM6
• Gene Symbols: TYW1B
• Immunogen: Recombinant protein corresponding to Human TYW1. Recombinant protein control fragment (Product #RP-102540).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov