Invitrogen™ U2AF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587918

Catalog No. PIPA587918

Description

Immunogen sequence: MAEYLASIFG TEKDKVNCSF YFKIGACRHG DRCSRLHNKP TFSQTIALLN IYRNPQNSSQ SADGLRCAVS DVEMQEHYDE FFEEVFTEME EKYGEVEEMN VCDNLGDHLV GNVYVKFRRE EDAEKAVIDL NNRWFNGQPI HAELSPVTDF REACCRQYEM GECTRGGFCN FMHLKPISRE LRRELYGRRR KKHRSRSRSR ERRSRSRDRG RGGGGGGGGG GGGRERDRRR SRDRERSGRF; Positive Samples: 22Rv1, Mouse spleen; Cellular Location: Nucleus, Nucleus speckle.

This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: U2AF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: U2AF1
• Gene Alias: 2010107D16Rik; 35kDa; FP793; RN; RNU2AF1; Splicing factor U2AF 35 kDa subunit; Splicing factor U2AF 35 kDa subunit-like protein; splicing factor U2AF 35kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF),35 kDa; U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit; U2 small nuclear RNA auxiliary factor 1; U2 small nuclear RNA auxiliary factor 1-like protein 5; U2 small nuclear RNA auxillary factor 1; U2 snRNP auxiliary factor small subunit; U2(RNU2) small nuclear RNA auxiliary factor binding protein; U2af1; U2AF1L5; U2AF35; U2AFBP
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 108121, 687575, 7307
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.24 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q01081, Q9D883
• Gene Symbols: U2AF1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human U2AF1 (NP_0067491).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG