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Invitrogen™ UAP1L1 Polyclonal Antibody
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Catalog No. PIPA569578
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PIPA569578 100 μL
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Catalog No. PIPA569578 Supplier Invitrogen™ Supplier No. PA569578
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 83%.

UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UAP1L1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene UAP1L1
Gene Accession No. Q3TW96
Gene Alias 5730445F03Rik; UAP1; uap1l1; UDP-N-acetylglucosamine pyrophosphorylase 1 like 1; UDP-N-acetylglucosamine pyrophosphorylase 1, like 1; UDP-N-acetylhexosamine pyrophosphorylase-like protein 1; UDP-N-acteylglucosamine pyrophosphorylase 1, like 1; UDP-N-acteylglucosamine pyrophosphorylase 1-like 1; zgc:56509
Gene Symbols UAP1L1
Host Species Rabbit
Immunogen synthetic peptide corresponding to a region of mouse UAP1L1 (aa 360-409).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227620
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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