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Invitrogen™ UAP1L1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA569578
Description
This target displays homology in the following species: Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 83%.
UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.
Specifications
UAP1L1 | |
Polyclonal | |
Unconjugated | |
UAP1L1 | |
5730445F03Rik; UAP1; uap1l1; UDP-N-acetylglucosamine pyrophosphorylase 1 like 1; UDP-N-acetylglucosamine pyrophosphorylase 1, like 1; UDP-N-acetylhexosamine pyrophosphorylase-like protein 1; UDP-N-acteylglucosamine pyrophosphorylase 1, like 1; UDP-N-acteylglucosamine pyrophosphorylase 1-like 1; zgc:56509 | |
Rabbit | |
Affinity chromatography | |
RUO | |
227620 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
Q3TW96 | |
UAP1L1 | |
synthetic peptide corresponding to a region of mouse UAP1L1 (aa 360-409). | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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