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UAP1L1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734821 Shop All Proteintech Group Inc Products
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50-173-4821 150 μL
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Catalog No. 50-173-4821 Supplier Proteintech Group Inc Supplier No. 252621AP150UL
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Rabbit Polyclonal Antibody

UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.

Specifications

Antigen UAP1L1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene UAP1L1
Gene Accession No. Q3KQV9
Gene Alias UAP1L1
Gene Symbols UAP1L1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91373
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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