UAP1L1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA571598

Catalog No. PIPA571598

Description

UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a α/β structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.

Specifications

• Antigen: UAP1L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UAP1L1
• Gene Alias: UDP-N-acetylhexosamine pyrophosphorylase-like protein 1; 277-; UAP1L1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 91373
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.52 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q3KQV9
• Gene Symbols: UAP1L1
• Immunogen: KLH conjugated synthetic peptide between 109-137 amino acids from the N-terminal region of human UAP1L1
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG