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Invitrogen™ UAP56 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597021

Catalog No. PIPA597021


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Description

Description

Immunogen sequence: RGMPQEERLS RYQQFKDFQR RILVATNLFG RGMDIERVNI AFNYDMPEDS DTYLHRVARA GRFGTKGLAI TFVSDENDAK ILNDVQDRFE VNISELPDEI DISSYIEQTR; Positive Samples: 293T, HeLa, LO2, SKOV3, K-562, SW620; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle.

This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UAP56
Polyclonal
Unconjugated
DDX39B
0610030D10Rik; 56 kDa U2AF65-associated protein; AI428441; ATP-dependent RNA helicase p47; Bat1; Bat-1; Bat1a; D17H6S81E; D17H6S81E-1; D20H6S81e; D6S81E; D6S81Eh; Ddx39b; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; DEAD-box helicase 39B; DExD-box helicase 39B; HLA-B associated transcript 1; HLA-B associated transcript 1A; HLA-B-associated transcript 1 protein; HLA-B-associated transcript 1A; Nuclear RNA helicase; nuclear RNA helicase (DEAD family); nuclear RNA helicase Bat1; p47; spliceosome RNA helicase BAT1; spliceosome RNA helicase DDX39B; Uap56
Rabbit
Affinity chromatography
RUO
114612, 53817, 7919
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1.5 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13838, Q63413, Q9Z1N5
DDX39B
Recombinant fusion protein containing a sequence corresponding to amino acids 319-428 of human UAP56/UAP56/DDX39B (NP_0046311).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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