Invitrogen™ UAP56 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527427

Catalog No. PIPA527427

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (97%), Xenopus laevis (96%), Dog (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.

Specifications

• Antigen: UAP56
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDX39B
• Gene Alias: 0610030D10Rik; 56 kDa U2AF65-associated protein; AI428441; ATP-dependent RNA helicase p47; Bat1; Bat-1; Bat1a; D17H6S81E; D17H6S81E-1; D20H6S81e; D6S81E; D6S81Eh; Ddx39b; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; DEAD-box helicase 39B; DExD-box helicase 39B; HLA-B associated transcript 1; HLA-B associated transcript 1A; HLA-B-associated transcript 1 protein; HLA-B-associated transcript 1A; Nuclear RNA helicase; nuclear RNA helicase (DEAD family); nuclear RNA helicase Bat1; p47; spliceosome RNA helicase BAT1; spliceosome RNA helicase DDX39B; Uap56
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114612, 53817, 7919
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.43 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q13838, Q63413, Q9Z1N5
• Gene Symbols: DDX39B
• Immunogen: Recombinant protein encompassing a sequence within the center region of human BAT1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG