Invitrogen™ UBA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527744

Catalog No. PIPA527744

Description

Recommended positive controls: HeLa. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (90%), Xenopus laevis (89%), Chicken (96%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

UBA2 is involved in covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.

Specifications

• Antigen: UBA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBA2
• Gene Alias: AA986091; Anthracycline-associated resistance ARX; Arx; EGK_10449; FLJ13058; HRIHFB2115; SAE2; SUMO1 activating enzyme subunit 2; Sumo-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; UBA1; UBA2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin like modifier activating enzyme 2; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier activating enzyme 2; ubiquitin-like modifier-activating enzyme 2; Ubl1a2; Uble1b
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10054
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UBT2
• Gene Symbols: UBA2
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human UBA2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov