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Invitrogen™ UBA2 Polyclonal Antibody
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Catalog No. PIPA527744
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100 μL
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PIPA527744 100 μL
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Catalog No. PIPA527744 Supplier Invitrogen™ Supplier No. PA527744
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (90%), Xenopus laevis (89%), Chicken (96%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

UBA2 is involved in covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBA2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene UBA2
Gene Accession No. Q9UBT2
Gene Alias AA986091; Anthracycline-associated resistance ARX; Arx; EGK_10449; FLJ13058; HRIHFB2115; SAE2; SUMO1 activating enzyme subunit 2; Sumo-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; UBA1; UBA2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin like modifier activating enzyme 2; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier activating enzyme 2; ubiquitin-like modifier-activating enzyme 2; Ubl1a2; Uble1b
Gene Symbols UBA2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human UBA2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10054
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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