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Invitrogen™ UBA2 Polyclonal Antibody
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Catalog No. PIPA580199
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100 μg
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PIPA580199 100 μg
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Catalog No. PIPA580199 Supplier Invitrogen™ Supplier No. PA580199
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human placenta tissue, human MCF-7 whole cell, human A549 whole cell, human SK-OV-3 whole cell, human 22RV1 whole cell, human A431 whole cell, human COLO-320 whole cell. IHC: human colon cancer tissue, human mammary cancer tissue, rat testis tissue, mouse testis tissue. ICC/IF: A431 cell. Flow: A431 cell.

UBA2 is involved in covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBA2
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene UBA2
Gene Accession No. Q9UBT2, Q9Z1F9
Gene Alias AA986091; Anthracycline-associated resistance ARX; Arx; EGK_10449; FLJ13058; HRIHFB2115; SAE2; SUMO1 activating enzyme subunit 2; Sumo-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; UBA1; UBA2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin like modifier activating enzyme 2; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier activating enzyme 2; ubiquitin-like modifier-activating enzyme 2; Ubl1a2; Uble1b
Gene Symbols UBA2
Host Species Rabbit
Immunogen E. coli-derived human SAE2/UBA2 recombinant protein (Position: E449-K564).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10054, 308508, 50995
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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