UBA3 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI1B10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811880

Catalog No. 50-167-0876

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: UBA3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: UBA3
• Gene Alias: NAE2, UBE1C, hUBA3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117553, 22200, 476560, 9039
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI1B10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8C878, Q8TBC4, Q99MI7
• Gene Symbols: Uba3
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-463 of human UBA3 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1