Invitrogen™ UBC3B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531003

Catalog No. PIPA531003

Description

Recommended positive controls: 293T, A431, Jurkat, Raji, mouse liver. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (94%), Xenopus laevis (99%), Chicken (99%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Specifications

• Antigen: UBC3B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE2R2
• Gene Alias: 1200003M11Rik; CDC34B; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R2; E2-CDC34B; LOC689226; similar to ubiquitin-conjugating enzyme E2R 2; UBC3B; Ube2r2; Ubiquitin carrier protein R2; ubiquitin conjugating enzyme E2 R2; ubiquitin conjugating enzyme E2R 2; ubiquitin-conjugating enzyme E2 R2; ubiquitin-conjugating enzyme E2-32k; ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; ubiquitin-conjugating enzyme UBC3B; ubiquitin-protein ligase R2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54926, 67615
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.69 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6ZWZ2, Q712K3
• Gene Symbols: UBE2R2
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 194 of Human UBC3B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov