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Invitrogen™ UBC3B Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA531003
Description
Recommended positive controls: 293T, A431, Jurkat, Raji, mouse liver. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (94%), Xenopus laevis (99%), Chicken (99%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
Specifications
UBC3B | |
Polyclonal | |
Unconjugated | |
UBE2R2 | |
1200003M11Rik; CDC34B; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R2; E2-CDC34B; LOC689226; similar to ubiquitin-conjugating enzyme E2R 2; UBC3B; Ube2r2; Ubiquitin carrier protein R2; ubiquitin conjugating enzyme E2 R2; ubiquitin conjugating enzyme E2R 2; ubiquitin-conjugating enzyme E2 R2; ubiquitin-conjugating enzyme E2-32k; ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; ubiquitin-conjugating enzyme UBC3B; ubiquitin-protein ligase R2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
54926, 67615 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot, Immunocytochemistry | |
0.69 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
Q6ZWZ2, Q712K3 | |
UBE2R2 | |
Recombinant protein fragment corresponding to a region within amino acids 1 and 194 of Human UBC3B. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
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