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Invitrogen™ UBE1 Polyclonal Antibody
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Catalog No. PIPA588493
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100 μL
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PIPA588493 100 μL
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Catalog No. PIPA588493 Supplier Invitrogen™ Supplier No. PA588493
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KISFKSLVAS LAEPDFVVTD FAKFSRPAQL HIGFQALHQF CAQHGRPPRP RNEEDAAELV ALAQAVNARA LPAVQQNNLD EDLIRKLAYV AAGDLAPINA FIGGLAAQEV MKACSGKFMP IMQWLYFDAL ECLPEDKEVL TEDKCLQRQN RYDGQVAVFG SDLQEKLGKQ KYFLVGAGAI GCELLKNFAM IGLGCGEGGE IIVTDMDTIE KSNLNRQFLF RPWDVTKLKS DTAAAAVRQM NPHIRVTSHQ NRVGPDTERI YDDDFFQNLD GVANALDNVD ARMYMDRRCV YYRKPLLESG T; Positive Samples: U-251MG, Rat spleen; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, Nucleus.

UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 23. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene UBA1
Gene Accession No. P22314, Q02053, Q5U300
Gene Alias A1S9; A1S9 protein; A1S9T; A1S9T and BN75 temperature sensitivity complementing; A1ST; AMCX1; CFAP124; EMBL:AAH85791.1, ECO:0000312; GXP1; POC20; POC20 centriolar protein homolog; Protein A1S9; RGD:1359327}; Sbx; SMAX2; testicular secretory protein Li 63; Uba1; uba1 {ECO:0000312; UBA1, ubiquitin-activating enzyme E1 homolog A; UBA1A; UBE1; Ube-1; Ube1ax; Ube1x; ubiquitin like modifier activating enzyme 1; Ubiquitin-activating enzyme E1; ubiquitin-activating enzyme E1 {ECO:0000250; Ubiquitin-activating enzyme E1 X; ubiquitin-activating enzyme E1, Chr X; ubiquitin-like modifier activating enzyme 1; ubiquitin-like modifier-activating enzyme 1; ubiquitin-like modifier-activating enzyme 1 {ECO:0000250; Ubiquitin-like modifier-activating enzyme 1 X; UniProtKB:Q02053}
Gene Symbols UBA1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human UBA1 (NP_6950121).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22201, 314432, 7317
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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