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Invitrogen™ UBE1L2 Polyclonal Antibody
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Catalog No. PIPA596707
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100 μL
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PIPA596707 100 μL
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Catalog No. PIPA596707 Supplier Invitrogen™ Supplier No. PA596707
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEGSEPVAAH QGEEASCSSW GTGSTNKNLP IMSTASVEID DALYSRQRYV LGDTAMQKMA KSHVFLSGMG GLGLEIAKNL VLAGIKAVTI HDTEKCQAWD LGTNFFLSED DVVNKRNRAE AVLKHIAELN PYVHVTSSSV PFNETTDLSF LDKYQCVVLT EMKLPLQKKI NDFCRSQCPP IKFISADVHG IWSRLFCDFG DEFEVLDTTG EEPKEIFISN ITQANPGIVT CLENHPHKLE TGQFLTFREI NGMTGLNGSI; Positive Samples: U-251MG, SKOV3, 293T, Mouse brain.

UBA6 (UBE1L2, MOP-4)is a novel E1 enzyme specific for ubiquitin and belongs to the ubiquitin-activating E1 family. It is a part of the cascade to attach ubiquitin (Ub) covalently to substrate proteins.UBA6 activates ubiquitin by first adenylating its carboxy-terminal glycine residue with ATP and then linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Its isoforms influence spermatogenesis and male fertility.UBA6 is highly expressed in human monocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE1L2
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene UBA6
Gene Accession No. A0AVT1, Q8C7R4
Gene Alias 4930542H01; 5730469D23Rik; AU021846; AW124799; E1-L2; Monocyte protein 4; MOP4; MOP-4; RGD1308324; UBA6; UBA6, ubiquitin-activating enzyme E1; Ube1l2; ubiquitin like modifier activating enzyme 6; ubiquitin-activating enzyme 6; ubiquitin-activating enzyme E1-like 2; ubiquitin-activating enzyme E1-like protein 2; ubiquitin-like modifier activating enzyme 6; ubiquitin-like modifier-activating enzyme 6
Gene Symbols UBA6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human UBA6 (NP_0606974).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 231380, 55236
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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